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Publications Here you can find all publications by our consortium partners that have been published with support from the NANOMMUNE grant (NMP-SL-2008-214281). | 2011 | | Safety of nanomedicines: the challenges ahead | | Nyström A.M. and Fadeel B. | | J Control Rel (in press) | | | | Shape and biocompatibility of nanoporous folic acid materials | | Zhou C, Kunzmann A, Rakonjac M, Fadeel B, Garcia-Bennett A. | | Nanomedicine (in press) | | | | Mapping the Surface Adsorption Forces of Nanomaterials in Biological Systems | | Xia XR, Monteiro-Riviere NA, Mathur S, Song X, Xiao L, Oldenberg S, Fadeel B, Riviere JE. | | ACS Nano 2011 Oct 16 [epub ahead of print] doi:10.1021/nn203303c | | Read » (opens in new window) | | | | Current status and future prospects of nanotechnology in cosmetics | | Mihranyan A, Ferraz N, Strømme M. | | Progress in Materials Science 2011 Oct 15 [epub ahead of print] doi:10.1016/j.pmatsci.2011.10.001 | | Read » (opens in new window) | | | | Interactions of carbon nanotubes with the immune system: focus on mechanisms of internalization and biodegradation | | Fadeel B, Shvedova AA, Kagan VE. | | Nanomedicine – Basic and Clinical Application in Diagnostics and Therapy. Editor: C. Alexiou. Else Kröner-Fresenius Symp. 2011, vol 2, pp 80-87 doi:10.1159/000328892 | | Read » (opens in new window) | | | | Synthesis of high aspect ratio gold nanorods and their effects on human antigen presenting dendritic cells | | Ye F., Vallhov H., Qin J., Daskalaki E., Sugunan A., Toprak M., Fornara A., Gabrielsson S., Scheynius A., Muhammed M. | | Int J Nanotechnology 2011;8(8/9):631-652 doi:10.1504/IJNT.2011.041435 | | Read » (opens in new window) | | | | A brief summary of carbon nanotubes science and technology: a health and safety perspective | | Wick P, Clift MJD, Roesslein M, Rothen-Rutishauser B. | | ChemSusChem 2011 Jul 18;4(7):905-11 doi:10.1002/cssc.201100161 | | Read » (opens in new window) | | | | SnO2-TiO2 Core-Shell Nanowire Structures: Investigation on Solid State Reactivity and Photocatalytic Behaviors | | Pan J,Hühne S-M, Shen H, Xiao L, Born P, Mader W, Mathur S. | | J. Phys. Chem C 2011 Sep;115(35):17265-17269 doi: 10.1021/jp201901b | | Read » (opens in new window) | | | | SiO2@Fe2O3 core-shell nanoparticles for covalent immobilization and release of sparfloxacin drug | | El-Gamel N, Wortmann L, Arroub K, Mathur S. | | Chem Comm 2011 Aug 30;47(36):10076-8 doi: 10.1039/c1cc13708e | | Read » (opens in new window) | | | | Global Phospholipidomics Analysis Reveals Selective Pulmonary Peroxidation Profiles Upon Inhalation of Single-Walled Carbon Nanotubes | | Tyurina Y, Kisin ER, Murray A, Tyurin VA, Kapralova VI, Sparvero LJ, Amoscato AA, Samhan-Arias AK, Swedin L, Lahesmaa R, Fadeel B, Shvedova AS, Kagan VE. | | ACS Nano 2011 Sep 27;5(9):7342-53 doi: 10.1021/nn202201j | | Read » (opens in new window) | | | | Carbon Nanotubes – Curse or Blessing | | Kaiser J-P, Roesslein M, Buerki-Thurnherr T, Wick P. | | Current Medicinal Chemistry 2011, 18: 2115-2128 | | | | Nanomaterial cell interactions: Are current in vitro tests reliable? | | Hirsch C, Roesslein M, Krug HF, Wick P. | | Nanomedicine (Lond). 2011 Jul;6(5):837-47 | | Read » (opens in new window) | | | | Synthesis, toxicology and potential of ordered mesoporous materials in nanomedicine | | Garcia-Bennett AE. | | Nanomedicine (Lond). 2011 Jul;6(5):867-77 doi: 10.2217/nnm.11.82 | | Read » (opens in new window) | | | | Water-Soluble Superparamagnetic Magnetite Nanoparticles with Biocompatible Coating for Enhanced Magnetic Resonance Imaging (MRI) | | Xiao L, Li J, Brougham DF, Fox EK, Feliu N, Bushmelev A, Schmidt A, Mertens N, Kiessling F, Valldor M, Fadeel B, Mathur S. | | ACS Nano. 2011 Aug 23;5(8):6315-24 doi:10.1021/nn201348s | | Read » (opens in new window) | | | | Solution engineered Pd-nanoparticles: model for health effect studies of automotive particulate pollution | | Wilkinson K, Palmberg L, Witasp E, Kupczyk M, Feliu N, Gerde P, Fadeel B, Seisenbaeva G, Dahlén S-E, Kessler V. | | ACS Nano 2011 Jul 26;5(7):5312-5324 doi: 10.1021/nn1032664 | | Read » (opens in new window) | | | | Direct effects of carbon nanotubes on dendritic cells induce immune suppression upon pulmonary exposure | | Tkach AV, Shurin GV, Shurin MR, Kisin ER, Murray AR, Young S-H, Star A, Fadeel B, Kagan VE, Shvedova AA. | | ACS Nano. 2011 Jul 26;5(7):5755-62 doi: 10.1021/nn2014479 | | Read » (opens in new window) | | | | Aluminophosphates for CO2 Separation | | Liu Q, Cheung NC, Garcia-Bennett AE, Hedin N. | | ChemSusChem. 2011 Jan 17;4(1):91-7 | | Read » (opens in new window) | | | | Efficient internalization of silica-coated iron oxide nanoparticles of different sizes by primary human macrophages and dendritic cells | | Kunzmann A, Andersson B, Vogt C, Feliu N, Ye F, Gabrielsson S, Toprak M, Thurnherr T, Laurent S, Vahter M, Krug H, Muhammed M, Scheynius A, Fadeel B. | | Toxicology and Applied Pharmacology 2011 Jun 1;253(2):81-93 doi: 10.1016/j.taap.2011.03.011 | | Read » (opens in new window) | | | | In search of the holy grail: Folate-targeted nanoparticles for cancer therapy | | Garcia-Bennett A, Nees M and Fadeel B. | | Biochem Pharmacol. 2011 Apr 15; 81(8): 976-984 | | Read » (opens in new window) | | | | Enzymatic degradation of multiwalled carbon nanotubes | | Zhao Y, Allen BL, Star A. | | J Phys Chem A 2011 Sep 1; 115(34):9536-44 doi:10.1021/jp112324d | | Read » (opens in new window) | | | | Comparative proteomics and pulmonary toxicity of instilled single-walled carbon nanotubes, crocidolite asbestos, and ultrafine carbon black in mice | | Teeguarden JG, Webb-Robertson BJ, Waters KM, Murray AR, Kisin ER, Varnum SM, Jacobs JM, Pounds JG, Zanger RC, Shvedova AA. | | Toxicol Sci. 2011 Mar;120(1):123-35. Epub 2010 Dec 6. doi: 10.1093/toxsci/kfq363 | | Read » (opens in new window) | | | | The enzymatic oxidation of graphene oxide | | Kotchey GP, Allen BL, Vedala H, Yanamala N, Kapralov AA, Tyurina YY, Klein-Seetharaman J, Kagan VE, Star A. | | ACS Nano. 2011 Mar 22;5(3):2098-108 | | Read » (opens in new window) | | | | Genotoxicity of carbon nanofibers: are they potentially more or less dangerous than carbon nanotubes or asbestos? | | Kisin E, Murray A, Sargent LM, Lowry D, Chirila M, Siegrist KJ, Schwegler-Berry D, Leonard S, Castranova V, Fadeel B, Kagan VE, Shvedova AA. | | Toxicol Appl Pharmacol 2011 Apr 1;252(1):1-10 | | Read » (opens in new window) | | | | Nanotoxicology: An Interdisciplinary Challenge | | Krug HF, Wick P. | | Angew Chem Int Ed Engl. 2011; 50:1260-78 | | Read » (opens in new window) | | | | A comparison of acute and long-term effects of industrial multiwalled carbon nanotubes on human lung and immune cells in vitro | | Thurnherr T, Brandenberger C, Fischer K, Diener L, Manser P, Maeder-Althaus X, Kaiser JP, Krug HF, Rothen-Rutishauser B, Wick P | | Toxicol Lett. 2011;200:176-86 | | Read » (opens in new window) | | | | 2010 | | Nanotoxicology: no small matter | Feliu N., Fadeel B. | Nanoscale 2010, Dec 1;2(12):2514-20 | Read » (opens in new window) | | Fantastic voyage and opportunities of engineered nanomaterials: what are the potential risks of occupational exposures? | Kagan V, Shi J, Feng W, Shvedova A, Fadeel B. | J Occup Environ Med 2010;52:943-946 | Read » (opens in new window) | | Probing cytotoxicity of gadolinium hydroxide nanostructures | Hemmer E, Kohl Y, Colquhoun V, Thielecke H, Soga K, Mathur S. | J Phys Chem B. 2010; 114:4358-65 | | Microwave Assisted Fast and Facile Synthesis of SnO2 Quantum Dots and Their Printing Applications | Xiao L, Shen H, von Hagen R, Pan J, Belkoura L, Mathur S. | Chemical Communication 2010; 46:6509-11 |
Read » (opens in new window) | | | | Quantitative Proteomics Analysis of the Nuclear Fraction of Human CD4+ Cells in the Early Phases of IL-4 Induced Th2 Differentiation | Moulder R, Lönnberg T, Elo LL, Filén JJ, Rainio E, Corthals G, Oresic M, Nyman TA, Aittokallio T, Lahesmaa R.
| Mol Cell Proteomics. 2010 [In press] | Read » (opens in new window) |
| | SATB1 dictates expression of multiple genes including IL-5 involved in human T helper cell differentiation | Ahlfors H, Limaye A, Elo LL, Tuomela S, Burute M, Gottimukkala K, Notani D, Rasool O, Galande S, Lahesmaa R.
| Blood 2010 [Epub ahead of print] | Read » (opens in new window) |
| | Toxicology of engineered nanomaterials: Focus on biocompatibility, biodistribution and biodegradation | Kunzmann A, Andersson B, Thurnherr T, Krug H, Scheynius A and Fadeel B.
| Biochim Biophys Acta. 2011 Mar;1810(3):361-73. Epub 2010 May 8. | Read » (opens in new window) |
| | Release of folic acid in mesoporous NFM-1 silica | Zhou, C and A. Garcia-Bennett | J. Nanoscience and Nanotechnology, 2010 Nov; 10(11): 7398-401 DOI: 10.1166/jnn.2010.2823 |
| | Carbon nanotubes degraded by neutrophil myeloperoxidase induce less pulmonary inflammation | V. E. Kagan, N. V. Konduru, W. Feng, B. L. Allen, J. Conroy, Y. Volkov, I. I. Vlasova, N. A. Belikova, N. Yanamala, A. Kapralov, Y. Y. Tyurina, J. Shi, E. R. Kisin, A. R. Murray, J. Franks, D. Stolz, P. Gou, J. Klein-Seetharaman, B. Fadeel, A. Star, A. Shvedova | Nature Nanotechnology, 2010 May;5(5):354-9. Epub 2010 Apr 4 | Read » (opens in new window) |
| | Better safe than sorry: Understanding the toxicological properties of inorganic nanoparticles manufactured for biomedical applications | B. Fadeel and A. E. Garcia-Bennett | Adv. Drug Deliv. Rev. 2010. Mar 8;62(3):362-374 | Read » (opens in new window) |
| | Close encounters of the small kind: adverse effects of man-made materials interfacing with the nano-cosmos of biological systems | A. A. Shvedova, V. E. Kagan and B. Fadeel | Annu Rev Pharmacol Toxicol. 2010;50:63-88 | Read » (opens in new window) |
| | Nanomedicine: reshaping clinical practice | B. Fadeel, B. Kasemo, M. Malmsten, and M. Strømme | J. Internal Medicine. 2010 Jan;267(1):2-8. | Read » (opens in new window) |
| | | | The role of nanotoxicology in realizing the 'helping without harm' paradigm of nanomedicine: lessons from studies of pulmonary effects of single-walled carbon nanotubes | A. A. Shvedova and V. E. Kagan | J Intern Med. 2010 Jan;267(1):106-18. PMID: 20059647. | Read » (opens in new window) |
| | 2009 | | Induction of aneuploidy by single-walled carbon nanotubes | Sargent LM, Shvedova AA, Hubbs AF, Salisbury JL, Benkovic SA, Kashon ML, Lowry DT, Murray AR, Kisin ER, Friend S, McKinstry KT, Battelli L, and Reynolds SH | Environ Mol Mutagen. 2009 Oct;50(8):708-17. | Read » (opens in new window) |
| | Mechanistic investigations of horseradish peroxidase-catalyzed degradation of single-walled carbon nanotubes | Allen BL, Kotchey GP, Chen Y, Yanamala NV, Klein-Seetharaman J, Kagan VE, and Star A. | J. Am. Chem. Soc., 2009, 131 (47): 17194–17205. | Read » (opens in new window) |
| Oxidative stress and inflammatory response in dermal toxicity of single-walled carbon nanotubes | Murray AR, Kisin E, Leonard SS, Young SH, Kommineni C, Kagan VE, Castranova V, and Shvedova AA | Toxicology 2009. Mar 29; 257(3):161-71. Epub 2008 Dec 30. | Read » (opens in new window) |
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Risk management of nanomaterials | M. R. Gwinn and L. Tran | Wiley interdisciplinary reviews- Nanomedicine and Nanobiotechnology 2009. DOI: 10.1002/wnan.57 | Read » (opens in new window) |
| | | Phosphatidylserine targets single-walled carbon nanotubes to professional phagocytes in vitro and in vivo | N. Konduru, Y. Tyurina, W. Feng, L. Basova, N. Belikova, H. Bayir, K. Clark, M. Rubin, D. Stolz, H. Vallhov, A. Scheynius, E. Witasp, B. Fadeel, P.D. Kichambare, A. Star, E.R. Kisin, A.R. Murray, A.A. Shvedova, and V.E. Kagan. | PLoS ONE 2009. 4(2): e4398. doi:10.1371/journal.pone.0004398 | Read » (opens in new window) |
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Size-dependent effects of tungsten carbide–cobalt particles on oxygen radical production and activation of cell signaling pathways in murine epidermal cells | M. Ding, E.R. Kisin, J. Zhao, L. Bowman, Y. Lu, B. Jiang, S. Leonard, V. Vallyathan, V. Castranova, A.R. Murray, B. Fadeel and A.A. Shvedova. | Toxicol. Appl. Pharmacol. 2009. 241(3) 260-268. | Read » (opens in new window) |
| | Comprehensive evaluation of in vitro toxicity of three large-scale produced carbon nanotubes on human Jurkat T cells and a comparison to crocidolite asbestos | Thurnherr, T., Su, D., Diener, L., Weinberg, G., Manser, P., Pfänder, N., Arrigo, R., Schuster, M. E., Wick, P., and Krug, H.F. Nanotoxicology. 2009. 3 (4) 319-338. |
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| | Efficient internalization of mesoporous silica particles of different sizes by primary human macrophages without impairment of macrophage clearance of apoptotic or antibody-opsonized target cells | E. Witasp, N. Kupferschmidt, L. Bengtsson, K. Hultenby, C. Smedman, S. Paulie, A.E. Garcia-Bennett, and B. Fadeel | Toxicol Appl Pharmacol. 2009 Sep 15. 239 (3): 306-319 | Read » (opens in new window) |
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| | Single-walled carbon nanotubes impair human macrophage engulfment of apoptotic cell corpses. | Witasp E, Shvedova AA, Kagan VE, and Fadeel B. | Inhal Toxicol. 2009 Jul;21 Suppl 1:131-6. | Read » (opens in new window) |
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| | Mass-spectrometric analysis of hydroperoxy- and hydroxy-derivatives of cardiolipin and phosphatidylserine in cells and tissues induced by pro-apoptotic and pro-inflammatory stimuli. | Tyurin VA, Tyurina YY, Jung MY, Tungekar MA, Wasserloos KJ, Bayır H, Greenberger JS, Kochanek PM, Shvedova AA, Pitt B, and Kagan VE. | J Chromatogr B Analyt Technol Biomed Life Sci. 2009 Mar 13 | Read » (opens in new window) |
| | | 2008 | | Mechanisms of pulmonary toxicity and medical applications of carbon nanotubes: Two faces of Janus? | Shvedova AA, Kisin ER, Porter D, Schulte P, Kagan VE, Fadeel B, and Castranova V | Pharmacol Ther. 2009 Feb;121(2):192-204. Epub 2008 Dec 6 | Read » (opens in new window) |
| | Increased accumulation of neutrophils and decreased fibrosis in the lung of NADPH oxidase-deficient C57BL/6 mice exposed to carbon nanotubes. | Shvedova AA, Kisin ER, Murray AR, Kommineni C, Castranova V, Fadeel B, and Kagan VE. | Toxicol. Appl. Pharmacol. 2008 Sep 1;231(2):235-40 | Read » (opens in new window) |
| | Inhalation vs. aspiration of single-walled carbon nanotubes in C57BL/6 mice: inflammation, fibrosis, oxidative stress, and mutagenesis. | Shvedova AA, Kisin E, Murray AR, Johnson VJ, Gorelik O, Arepalli S, Hubbs AF, Mercer RR, Keohavong P, Sussman N, Jin J, Yin J, Stone S, Chen BT, Deye G, Maynard A, Castranova V, Baron PA, and Kagan VE. | Am. J. Physiol. Lung Cell Mol. Physiol. 2008 Oct; 295(4):552-65 | Read » opens in new window) |
| | Oxidative stress and inflammatory response in dermal toxicity of single-walled carbon nanotubes. | Murray AR, Kisina E, Leonard SS, Young SH, Kommineni C, Kagan VE, Castranova V, and Shvedova AA. | Toxicology. 2008 Dec 30. | Read » (opens in new window) |
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